Dr. Marc De Graef is Professor of Materials Science and Engineering at Carnegie Mellon University. Over the past two decades, Prof. De Graef’s research group has been at the forefront of developing the numerical tools that allow us to convert raw experimental data from serial sectioning experiments into accurate 3D reconstructions. The group has developed a simulation technique that relies on basic physics to model the scattering of electrons in materials and the subsequent formation of an EBSD pattern. Ongoing work involves machine-learning approaches to speed up the new technique and turn it into a near-real-time indexing engine. De Graef’s research group has also contributed extensively to the field of Lorentz microscopy.